Welcome to Johns Hopkins Microarray Core Facility

Overview

Our aim is to provide cost-effective and time-efficient access to microarray technology, as well as an environment that facilitates effective analysis and sharing of microarray data. Data and information supplied by the Core are intended for research use only. This facility is not certified to supply data to be used in clinical care.

Organization of the Johns Hopkins Microarray Core Facility

The JHMI Microarray Core Facility is located in 3rd floor of Broadway Research Building (BRB), Room 351, and the hybridization lab located in Room 360, just across the hallway. It consists of two functionally separate units: Hybridization Unit and Analysis Unit. The Hybridization Unit currently provides labelled target production, hybridization, and data collection services for Affymetrix and other commercial arrays. The Analysis Unit offers support for data analyses from almost all array platforms, provides access to commercially available software through shared seat licensing, and maintains a shared-access microarray database. Although open access data transfer is encouraged, confidential storage is also supported.

Johns Hopkins Microarray Core Facility Support

We are grateful for the support from

The School of Medicine Office of the Dean
Institute of Cell Engineering (ICE)
Institute of Basic Biomedical Sciences (IBBS)
McKusick-Nathans Institute of Genetic Medicine (IGM)

for the organization of startup funds, space, and personnel. It is our goal to keep user fees as low as possible in order to encourage the growth of the Hopkins microarray research community.

News

May 1, 2008
New version of Spotfire 9.1.1 is available. Interested users please contact Microarray Core or fill out a account request form.
March 1, 2008
Partek Genomics Suite is available on the workstations on Room 343 BRB;
Febuary 1, 2008
Microarray core hybridization unit announces new lower prices for our most popular array services and new services added to our portfolio.

Working closely with Affymetrix, we have achieved a sizeable price reduction on all transcription and exon arrays. The price reduction ranges from $45.00 to $400 depends on the arrays and the type of processing protocol. For details on specific type of arrays, please see our newly updated fee schedule. The new prices are effective Feb. 1, 2008.

Please note that these price reductions are made possible in part by switching to reagent supplied by Affymetrix. This entails a slight change in our protocol. For samples requiring our archived protocol, we will be happy to provide the service with service fee at previous level. The change in protocol will not affect the quality of the data and the same high quality service will be maintained.

We have also added the following new services to our portfolio:
1. Nugen amplification processing for small samples down to 10 ng.
2. Exon 1.0ST and Gene 1.0ST arrays for whole transcript expression analysis, exon utilization analysis, and alternate splicing event analysis.
3. Tiling arrays for whole genome transcript mapping.
4. Tiling arrays and promoter arrays for ChIP-on-chip analyiss.
5. Tiling arrays for Copy Number Variance (CNV) analysis.
6. Two-color arrays for aCGH, microRNA, and other small array analysis.
7. real-time PCR for candidate validations and PCR array pathway analysis.
November 1, 2007
Microarray Core computer room (BRB 343) has the latest version of Stratagene software installed, ArrayAssist 5.5.1 and PathwaArchitect 3.0.1.
Ocbober 29, 2007
Welcome Haiping Hao!
Dr. Haiping Hao is the new manager for the Microarray Core Lab.
October 9, 2007
Analysis Unit institutes a much needed rate hike on Oct 10, 2007 to help meet its costs. The new rate for consultation and analysis requests is $85/hr.
April 5, 2007
PathArt has been upgraded to 2007 Release 1.Go to JHMI Microarray Core's PathArt Server. (within Hopkins networks only)
Jan. 16, 2007
PathwayArchect and ArrayAssist Software Packages (from Stratagene) are accessible from Hopkins campuses. Details in the software page;
Jan. 9, 2007
We are now running PathArt 2006R4. Go to JHMI Microarray Core's PathArt Server. (within Hopkins networks only)
Aug. 20, 2006
PathArt 2006 R2 is available within Hopkins campuses.
May 2, 2006
GeneSpring license renewed and license server software upgraded; GeneSpring Users can upgrade to GeneSpring GX 7.3.1;
June 15, 2005
JHMI Microarray Core has started running its own Spotfire DecisionSite Server version 8.1 . Interested users should refer to the How to download and install Spotfire document for details about its access.
Dec.16, 2004
Affymetrix announces changes in array production of older generation of GeneChip®, U95, U34, U74,etc.. See details;
Nov. 17, 2004
A new way to access GeneSpring License Server, that will avoid the Mutiple session message that stops GeneSpring running on your desktop. Please read the GeneSpring installation docs for Microsoft Windows or Mac OS X for details.
May 15, 2004
Hybridization Lab moves to Room 358 BRB. JHMI Microarray Core Facility is in a single location now!
March 26, 2004
Analysis Unit moves to Room 351, Broadway Reserch Building (BRB).
Feb. 25, 2004
New requistion form online!
Feb. 16, 2004
Microarray Core's FTP site launched! Users who have used hybridization unit can download their data. For details please click here or the "FTP server" link on the left menu.
Jan. 8, 2004 Analysis Unit has moved to Room 527, Broadway Research Building. Most of the services (including Microarray core facility web site and GeneSpring license server) are back to normal.
Analysis Unit has moved!
Starting 12/16/03, Microarray Core's Analysis Unit is moving from its Jefferson St.Building location to the its temporary quarter located at Broadway Research Building (BRB) room 527.
7/16/03, 9am-12pm - Microarray Core hosts the BioDiscovery "Statistical Analysis of Gene Expression for Microarray Data" seminar.
12/04/02 - Microarray Core hosts the Spotfire for Microarray Data Analysis presentation.
10/28/02 - 10/29/02 - Microarray core presents the BioConductor Workshop for Microarray Data Analysis.
9/3/02 - Analysis Unit starts to offer services on a trial basis for free! We provide both the access and technical help for some of the most popular packages like GeneSpring, Spotfire, and Biodiscovery suite (ImaGene and GeneSight) . You can find more details under the software menu on the left.
1/30/02 - Official opening Microarray Core
1/09/02 - Hybridization Unit initiates service

Last modified: Fri May 2 2008